Comparison of Cellular Alterations in Fat Cells Harvested With Laser-Assisted Liposuction and Suction-Assisted Liposuction

Objective: The aim of the present study was to evaluate theviability and proliferative capacity of adipose-derived stem cellsobtained by laser-assisted liposuction (LAL).Methods: Fat tissue was obtained from 7 male patients treatedsurgically for gynecomastia. On one side, harvesting was madebefore LAL, while it was implemented after LAL on thecontralateral side. Viability, cell surface antigens, pluripotency,and apoptosis were assessed and compared in these samples.Results: Cells harvested before and after LAL did not exhibit anysignificant difference in terms of surface cell markers. Number of viablestem cells was lower initially after exposure to laser, while thisdifference was reversed at the end of 72 hours. Genetic indicators ofcellular differentiation were similarin both groups. Apoptosisindicatorswere increased remarkably after laser exposure in the first 24 hours, butthis increase was absent 72 hours after LAL procedure.Conclusion: The authors’ results have promising clinical relevancesince mesenchymal stem cells harvested during LAL havemaintained appropriate cellular features to be used forautologous fat transfer and fat grafting.

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